Hasstedt > PAP (Pedigree Analysis Package) v6.0

Description

PAP is a package of programs for computing likelihoods or simulating phenotypes on pedigree members using genetic models. Version 6.0 is the final release in a long line of console-driven implementations. The package may be used for segregation analysis, variance components analysis, linkage analysis, measured genotype analysis, transmission disequilibrium testing, or genetic model fitting. It is distributed as the FORTRAN source. A large suite of examples, keyed to the manual, is included.

Due, among other reasons, to PAP's size, complexity, and system restrictions, we have found it requisite to transition to a Java-based implementation as development moves forward. An early version of the new implementation, which features a document-driven graphical interface and component-based design, is now available. Most users will prefer it to PAP 6.0, though the latter will remain available as an alternative for the foreseeable future.

System Requirements

While knowledgeable users may successfully adapt PAP 6.0 to other environments, it is packaged for use on Unix or a Unix-like system. A FORTRAN compiler must be available on the system both for installation and ongoing usage. We have found the g77 compiler, part of the free GNU gcc distribution, to work fine for this purpose under Linux and Solaris.

Download PAP v6.0 Patch 1 - Mar 26, 2007<

PAP 6.0 (Patch 1) (GZipped Tar - 131K)

Source code and makefile, plus examples.

Download PAP v5.0 (May 2002)

PAP 5.0 (GZipped Tar - 131K)

Source code and makefile, plus examples.

Documentation (PDF - 406K)

Complete 116-page manual.